Chinese scientists produced synthetic starch from carbon dioxide (CO_2) for the first time. Making possible industrial production.
Source: Phys.org
The new route makes it possible to shift the mode of starch production from traditional agricultural planting to industrial manufacturing, and opens up a new technical route for synthesizing complex molecules from CO2.
Starch is the major component of grain as well as an important industrial raw material. At present, it is mainly produced by crops such as maize by fixing CO2 through photosynthesis. This process involves about 60 biochemical reactions as well as complex physiological regulation. The theoretical energy conversion efficiency of this process is only about 2%.
Scientists at the Tianjin Institute of Industrial Biotechnology (TIB) of the Chinese Academy of Sciences (CAS) designed a chemoenzymatic system as well as an artificial starch anabolic route consisting of only 11 core reactions to convert CO2 into starch.
This route was established by a “building block” strategy, in which the researchers integrated chemical and biological catalytic modules to utilize high-density energy and high-concentration CO2 in a biotechnologically innovative way.
![synthetic starch production cycle](https://www.electricalelibrary.com/wp-content/uploads/2021/09/keyimage-1.gif)
The researchers systematically optimized this hybrid system using spatial and temporal segregation by addressing issues such as substrate competition, product inhibition, and thermodynamical adaptation.
The artificial route can produce starch from CO2 with an efficiency 8.5-fold higher than starch biosynthesis in maize, suggesting a big step towards going beyond nature. It provides a new scientific basis for creating biological systems with unprecedented functions.
“According to the current technical parameters, the annual production of starch in a one-cubic-meter bioreactor theoretically equates with the starch annual yield from growing 1/3 hectare of maize without considering the energy input,” said Cai Tao, lead author of the study.
“If the overall cost of the process can be reduced to a level economically comparable with agricultural planting in the future, it is expected to save more than 90% of cultivated land and freshwater resources,” said MA Yanhe, corresponding author of the study.
In addition, it would also help to avoid the negative environmental impact of using pesticides and fertilizers, improve human food security, facilitate a carbon-neutral bioeconomy, and eventually promote the formation of a sustainable bio-based society.
TIB has focused on artificial starch biosynthesis and CO2 utilization since 2015. To carry out such demand-oriented S&T research, all kinds of resources for innovation have been gathered together and the integration of “discipline, task and platform” has been strengthened to achieve efficient coordination of research efforts.